Find more resources in the Cochrane Community. What is osteoarthritis and what is diacerein? In OA, the cartilage that protects the ends of the slow acting drugs osteoarthritis breaks down, causing pain and swelling.
OA can affect any joint, but the knees, hips and hands are the joints most often studied in clinical trials. 60 or older have pain or disability from OA. Diacerein is a slow-acting drug taken as a pill that may slow the breakdown of cartilage and relieve pain and swelling. In the broader healthcare context it refers to any attempt to synthesise the results of more than one study on a particular topic area. Pain may improve slightly more in people taking diacerein.