Rheumatoid arthritis criteria 2010

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In the broader healthcare context it refers to any attempt to synthesise the results of more than one study on a particular topic area. The term research means different things to different people, but is essentially about finding out new knowledge that could lead to changes to treatments, policies or care. The attempt to derive generalisable new knowledge by addressing clearly defined questions with systematic and rigorous methods. An inflammatory condition of joints and tendons. Can be very painful and debilitating. An intervention that to all intents and purposes appears to be the same as that which is being assessed but which does not have the active component being assessed. This makes your joints swollen, stiff and painful.

The small joints of your hands and feet are usually affected first. They can be taken in a pill form, as an injection or as a patch placed on the skin. An adverse effect may be caused by administration of a medication or by exposure to a chemical and be indicated by an untoward result such as by illness or death. There is insufficient evidence to draw conclusions regarding the use of weak opioids for longer than six weeks, or the role of strong opioids. The group in a study that does not receive the intervention that is being investigated. Controls may receive no intervention, a placebo, a commonly used treatment for that condition, or only a part of an intervention.

The ability of an intervention to produce a desired effect in a controlled study. An American based electronic database listing articles of biomedical research from a pre-determined range of peer-reviewed publications. A method based on chance alone by which study participants are assigned to a treatment group. Randomization minimizes the differences among groups by equally distributing people with particular characteristics among all the trial arms. The researchers do not know which treatment is better.

From what is known at the time, any one of the treatments chosen could be of benefit to the participant. The treatment of disorders or disease. Data is the information collected through research. It can include written information, numbers, sounds and pictures. It is usually stored on computer, so that it can be analysed, interpreted and then communicated to others, for example in reports, graphs or diagrams. A way of expressing the chance of an event taking place, expressed as the number of events divided by the total number of observations or people. This measure is good no matter the incidence of events ie common or infrequent.

Any factor, recognised or not, that distorts the findings of a study. Data analysis involves examining and processing research data, in order to answer the questions that the project is trying to address. It involves identifying patterns and drawing out the main themes, and is often done with specialist computer software. A systematic, well-planned investigation of a healthcare problem.

Drug used to relieve pain. A measure expressed by the risk of an event in the group receiving the intervention divided by the risk in the control group. A compared to treatment B. The narrower the interval, the more precise the estimate. There is bound to be some uncertainty in estimates because studies are conducted on samples and not entire populations. CI includes the value of one in its range, we can say that there is no difference between the groups. This confidence interval tells us that, at least some of the time, the ratio of effects between the groups is one.