Find more resources in the Cochrane Community. In the broader osteoarthritis womac score context it refers to any attempt to synthesise the results of more than one study on a particular topic area.
The term research means different things to different people, but is essentially about finding out new knowledge that could lead to changes to treatments, policies or care. The attempt to derive generalisable new knowledge by addressing clearly defined questions with systematic and rigorous methods. What is osteoarthritis and glucosamine? In OA, the cartilage that protects the ends of the bones breaks down and causes pain and swelling. Glucosamine can be found naturally in the body and is used by the body as one of the building blocks of cartilage. Glucosamine can also be taken as a pill as a supplement to the diet, or sometimes as an injection. The usual dose recommended on packages is 1500 mg per day or 500 mg three times a day.
In Europe, glucosamine is prescribed by health care providers. But in North America, people can buy glucosamine supplements without a prescription. This means that, in North America, glucosamine is not regulated and the pills may or may not truly contain the amount described on the label. Pain: The high quality studies showed that pain improved about the same whether people took glucosamine or fake pills. People who took fake pills had a pain score of 7 points on a 0 to 100 scale. Pain may improve by 10 more points with glucosamine than with fake pills.