First sign arthritis issues related to DMARD therapy. Duration of morning stiffness not exceeding 15 minutes.
No symptoms of joint pain. No joint tenderness or pain on motion. No soft tissue swelling in joints or tendon sheaths. Require 5 or more for at least 2 consecutive months.
DMARDS, but this is not predictable from an individual perspective. These are summarized in tables 5 and 6. These are summarized in Table 7. Visual analogue scores for pain and stiffness.
Physician assessment visual analogue scores. Patient global assessment visual analogue scores. Methotrexate is given as an Injectable or oral preparation. To prevent nausea, doses should be administered in the evening. Use of folic acid does not interfere with drug activity and is given daily.
AST, ALT, GGT and full blood count. 1930′ s at Karolinska Institute by Prof. 1 g daily for one week, then 1. 5 g daily for one week, and thereafter 2 g per day. Response takes between 1-6 months. An enteric form is advised to further reduce gastric side effects.