Based on previous OA eular recommendations management rheumatoid arthritis and a systematic review of the OA literature, 29 treatment modalities were considered for recommendation. Tufts Medical Center, Boston, USA. Medline, EMBASE, Google Scholar, Web of Science, and the Cochrane Central Register of Controlled Trials were initially searched in first quarter 2012 and last searched in March 2013.
To provide recommendations for individuals with a range of health profiles and OA burden, treatment recommendations were stratified into four clinical sub-phenotypes. UCLA Appropriateness Method and Delphi voting process. 10 risk and benefit scores. These evidence-based consensus recommendations provide guidance to patients and practitioners on treatments applicable to all individuals with knee OA, as well as therapies that can be considered according to individualized patient needs and preferences. 2014 Osteoarthritis Research Society International. Synthetic DMARDs may be used as monotherapy or in combination, and can be co-prescribed with low-dose corticosteroids if necessary. Biologic DMARD therapy should be considered for patients who have failed a 6-month trial of at least 3 synthetic DMARDs.
These recommendations provide practical suggestions for the screening and management of TB and other comorbidities, and offer an approach to monitoring of RA patients. Copyright of published material remains in the Authors’ name. This allows authors to use their work for their own non-commercial purposes without seeking permission from the Publisher, subject to properly acknowledging the Journal as the original place of publication. Authors are free to copy, print and distribute their articles, in full or in part, for teaching activities, and to deposit or include their work in their own personal or institutional database or on-line website. Please inform the editorial team if the main findings of your paper have been presented at a conference and published in abstract form, to avoid copyright infringement. 6-month trial of at least 3 synthetic DMARDs.
Algorithm for management of rheumatoid arthritis in SA. RA than the previous ACR criteria. ACR 20, ACR 50 or ACR 70 response. MTX for moderate to severe disease. DMARDs have controlled the disease. SA, there is no reliable test for LTBI.
TST and IGRA may be the best strategy. CXR, should be given anti-TB chemoprophylaxis. 808 per 100 000 in the general population. Felty’s syndrome, and low socio-economic status.
TB, but cases have been reported. 25 and 29 years infected in 2010. RA, especially in post-menopausal women. RA tends to improve during pregnancy. GCs may be adequate to control symptoms.
DMARD therapy is summarised in Table 4. CXR, abdominal ultrasound and bone marrow aspiration. 9 statements on management of RA. ACR 50 response in a 70 kg subject. RA outweigh the costs of therapy.
RA management in our unique SA situation. DMARDs, and the risk factors for development of TB. RA in SA are needed. Y, Voulgari PV, Drosos AA. Rheumatology criteria: A systematic review. L, Robin G, Valkenburg HA.
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