C reactive protein and rheumatoid arthritis

Find out what it means when you have an elevated level. What Does the CRP Test Reveal About Arthritis? In the body, CRP c reactive protein and rheumatoid arthritis with the complement system, an immunologic defense mechanism.

An elevated CRP test result is an indication of acute inflammation. CRP test to assess the effectiveness of a specific arthritis treatment and monitor periods of disease flare-up. Its value is as a general indicator, though, not specific. By «not specific», it is meant that the CRP test does not reveal what is causing inflammation in the body.

It simply indicates that there is inflammation. With inflammatory disease, a low CRP level is possible. While that seems counterintuitive, a low CRP level does not necessarily indicate that there is no inflammation present. While it is true that CRP levels may not be increased in some people diagnosed with rheumatoid arthritis or lupus, the reason is unknown.

From Lab Tests Online, «A high or increasing amount of CRP in the blood suggests the presence of inflammation but will not identify its location or the condition causing it. In individuals suspected of having a serious bacterial infection, a high CRP suggests the presence of one. In people with chronic inflammatory conditions, high levels of CRP suggest a flare-up or that treatment has not been effective. Both CRP and ESR yield non-specific information about inflammation.

One notable difference between the two tests is that changes are reflected more quickly with CRP compared to ESR. For example, your CRP level may drop to normal following successful treatment more quickly, while ESR remains elevated for a longer period. The hs-CRP measures very low amounts of CRP in the blood and is typically used to assess risk for heart problems. With the regular CRP test, the normal reference range may vary from laboratory to laboratory. As a general rule, there is no CRP detectable in normal blood. With the hs-CRP test, a result of lower than 1.